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Literature
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| Caspase Papers |
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Hardy, J. A., Lam, J., Nguyen, J. T., O’Brien, T. and Wells, J. “Discovery of an allosteric site in caspases.” Proc. Natl. Acad. Sci. U S A. 2004, 101(34), 12461-6. |
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| Protein Design Papers |
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Hardy, J. A. and Nelson, H. C. M. “Proline in an alpha-helical kink is required for folding kinetics but not for kinked structure, function or stability of heat shock transcription factor” Protein Science, 2000, 9(11), 2128-2141. |
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Hardy, J. A., Walsh, S. T. R., and Nelson, H. C. M. “Role of an alpha-Helical Bulge in the Yeast Heat Shock Transcription Factor” J. Mol. Biol., 2000, 295(3), 393-409. |
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| Allosteric Papers |
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Hardy, J. A. and Wells, J. “Searching for Allosteric Sites in Enzymes.” Curr. Opin. Str. Biol. 2004, 14(6), 706-715. |
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Hardy, J.A. "Discovery and exploitation of allosteric sites for control of protein function." Nanomedicine: Nanotechnology, Biology and Medicine 2006, 2(4), 291. |
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Hardy, J. A. “A Link Means a Lot: Disulfide Tethering in Structure-Based Drug Design” in Computational Approaches to Structure Based Drug Design, publishers Royal Society of Chemistry, 2007, 318-347. |
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Funding |
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Smith Family Young Investigator Award from The Medical Foundation 2005-2007 |
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Beckman Young Investigator Award from the Arnold and Mabel Beckman Foundation 2006-2009 |
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American Cancer Society Grant 2006-2007 |
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NSF Chemical Bonding Center "Fueling the Future" 2007-2010 |
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NIH R01 Grant 2008-2013 |
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NSM Excellence Initiative Grant 2008 |
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Lab Updates
Hardy Named Cottrell Scholar by Research Corp.
Hardy Lab funded by R01 grant from NIH.
Sam Bernard Awarded NSF IGERT traineeship from the Institute for Cellular Engineering
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