Publications

(47) Pektas, S.; Taabazuing, C. Y.; Knapp, M. J. “Increased Turnover at Limiting O2 Concentrations by the Thr387Ala Variant of HIF-Prolyl Hydroxylase PHD2,“  Biochemistry, (accepted)

(46) Hangasky, J. A.; Gandhi, H.; Valliere, M. A.; Ostrom, N. E.; Knapp, M. J. “The Rate-Limiting Step of O2 activation in the a-Ketoglutarate Oxygenase Factor Inhibiting Hypoxia Inducible Factor,“  Biochemistry, 2014, 53, pp 8077–8084

(45) Hangasky, J. A.; Ivison, G. T.; Knapp, M. J. “Substrate Positioning by Gln239 Stimulates Turnover in Factor Inhbiting HIF, an aKG-dependent hydroxylase,“  Biochemistry, 2014, 53, pp 5750–5758

(44) Taabazuing, C. Y.; Hangasky, J. A.; Knapp, M. J. “Oxygen Sensing Strategies in Mammals and Bacteria,“  J. Inorg. Biochem. 2014, 133, pp 63–72

(43) Light, K. M.; Hangasky, J. A.; Knapp, M. J.; Solomon, E. I. “First- and second-sphere contributions to Fe(II) site activation by cosubstrate binding in non-heme Fe enzymes,“  Dalton Trans., 2014, 43, pp 1505–1508

(42) Light, K. M.; Hangasky, J. A.; Knapp, M. J.; Solomon, E. I. “Spectroscopic Studies of the Mononuclear Nonheme Fell Enzyme FIH: Second-Sphere Contributions to Reactivity,“  J. Amer. Chem. Soc., 2013, 135 (26), pp 9665–9674

(41) Pektas, S.; Knapp, M. J. “Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change,“  J. Inorg. Biochem., 2013, 126, pp 55–60

(40) Hangasky, J. A.; Taabazuing, C. Y.; Valliere, M. A.; Knapp, M. J. “Imposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the alpha KG dependent oxygenases ,“  Metallomics, 2013, 5 (4), pp 287–301

(39) Hangasky, J. A.; Saban, E.; Knapp, M. J. “Inverse Solvent Isotope Effects Arising from Substrate Triggering in the Factor Inhibiting Hypoxia Inducible Factor,“  Biochemistry, 2013, 52 (9), pp 1594–1602

(38) Flagg, S. C.; Martin, C. B.; Taabazuing, C. Y.; Knapp, M. J. “Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH),“  J. Inorg. Biochem., 2012, 113, pp 25–30

(37) Flagg, S. C.; Giri, N.; Pektas, S.; Maroney, M. J.; Knapp, M. J. “Inverse Solvent Isotope Effects Demonstrate Slow Aquo Release from Hypoxia Inducible Factor-Prolyl Hydroxylase (PHD2),“  Biochemistry, 2012, 51 (33), pp 6654–6666

(36) Saban, E.; Chen, Y.-H.; Hangasky, J. A.; Taabazuing, C. Y.; Holmes, B. E.; Knapp, M. J. “The Second Coordination Sphere of FIH Controls Hydroxylation,“  Biochemistry, 2011, 50 (21), pp 4733–4740

(35) Saban, E.; Flagg, S. C.; Knapp, M. J. “Uncoupled O-2 activation in the human HIF-asparaginyl hydroxylase, FIH, does not produce reactive oxygen species,“  J. Inorg. Biochem., 2011, 105 (5), pp 630–636

(34) Meaghan E. Germain, Michael J. Knapp. “Optical explosives detection: from color changes to fluorescence turn-on,“  Chem. Soc. Rev., 2009, 38 (9), pp 2543–2555

(33) Adrienne Carver, Michael J. Knapp. “Intermolecular electron-transfers in protein/nanoparticle hybrids,“  J. Am. Chem. Soc., 2009, 237

(32) Carver, A. C.; De, M.; Bayraktar, H.; Rana, S.; Rotello, V. M.; Knapp, M. J.* “Intermolecular Electron-Transfer Catalyzed on Nanoparticle Surfaces,“  J. Am. Chem. Soc., 2009, 131 (11), pp 3798–3799

(31) Carver, A. C.; Knapp, M. J.* "Electron and energy transfer reactions of [Ru(bpy)3]2+*/3+ with copper-phenolates," Polyhedron 200827, 3313

(30) Chen, Y.-H.; Comeaux, L. M.; Herbst, R. M.; Saban, E.; Kennedy, D. C.; Maroney, M. J.; Knapp, M. J.* "Coordination changes and auto-hydroxylation of FIH-1: uncoupled O2-activation in a human hypoxia sensor," J. Inorg. Biochem. 2008, accepted for a special “Young Investigators Issue.” J. Inorg. Biochem.
Volume 102, Issue 12, December 2008, 2120-2129

(29) Germain, M. E.; Knapp, M. J.* "Turn-on fluorescence detection of H2O2 and TATP," Inorg. Chem., 2008, 47 (21), pp 9748–9750.

(28) Germain, M. E.; Vargo, T. R.; McClure, B. A.; Rack, J. J.; Van Patten, P. G.; Odoi, M.; Knapp, M. J.* "Quenching Mechanism of Zn(Salicylaldimine) by Nitroaromatics," Inorg. Chem. 2008, 47, 6203-6211.

(27) Germain, M. E.; Knapp,* M. J. “Discrimination of nitroaromatics and explosives mimics by a fluorescent Zn(salicylaldimine) sensor array”,  J. Am. Chem. Soc. 2008 130 (16), 5422

(26) Chen, Y.-H.; Comeaux, L. M.; Eyles, S. J.; Knapp, M. J. "Auto-hydroxylation of FIH-1, an Fe(II), α-ketoglutarate dependent human hypoxia sensor, " Chem. Commun. 2008

(25) Bayraktar, H, Srivastava, S.; You, C.-C.; Rotello,* V. M.; Knapp,* M. J. “Controlled nanoparticle assembly through protein conformational changes,” Soft Matter 2008 4, 751-756  (cover article)

   

   (24) Bayraktar, H.; You, C.-C.; Rotello, V. M.; Knapp, M. J. "Facial Control of Nanoparticle Binding to Cytochrome c" J.      Am. Chem. Soc., 2007, 129, 2732-2733.
   

(23) Meaghan E. Germain, Thomas R. Vargo, Peter G. Khalifah and Michael J. Knapp, “Fluorescent detection of nitroaromatics and 2,3-dimethyl 2,3-dinitrobutane (DMNB) by a zinc complex: (L)Zn” Inorg. Chem., 2007, 46, 4422-4429

(22) Britto S. Sandanaraj, Halil Bayraktar, Kothandam Krishnamoorthy, Michael J. Knapp and Sankaran Thayumanavan, “Recognition and Modulation of Cytochrome c's Redox Properties by an Amphiphilic Homopolymer”  Langmuir, 2007, 23, 3891-3897

(21) You, C.-C.; Agasti,S. S.; De, M.; Knapp, M. J.; Rotello, V. M.; "Modulation of the Catalytic Behavior of a-Chymotrypsin at Monolayer-Protected Nanoparticle Surfaces," J. Am. Chem. Soc., 2006, 128, 14612-14618.

(20) Bayraktar, H.; Ghosh, P. S.; Rotello, V. M.; Knapp, M. J. "Disruption of protein-protein interactions using nanoparticles: inhibition of cytochrome c peroxidase," Chem. Comm. 2006, 13, 1390-1392.

(19) Knapp, M. J.; Meyer, M. M.; Klinman, J. P. In Handbook of Hydrogen Transfer, Vol; 2: Biological Aspects of Hydrogen Transfer; Schowen, R. L., Klinman, J. P., Eds.; Wiley VCH: Weinheim, 2006.

(18) Knapp, M. J.; Klinman, J. P. "Kinetic studies of oxygen reactivity in soybean lipoxygenase-1," Biochemistry 2003, 42, 11466-11475.

(17) Sanudo, E. C.; Grillo, V. A.; Knapp, M. J.; Bollinger, J. C.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. "Tetranuclear manganese complexes with dimer-of-dimer and ladder structures from the use of a bis-bipyridyl ligand," Inorg. Chem. 2002, 41, 2441-2450.

(16) Francisco, W. A.; Knapp, M. J.; Blackburn, N. J.; Klinman, J. P. "Hydrogen tunneling in peptidylglycine alpha-hydroxylating monooxygenase," J. Am. Chem. Soc. 2002, 124, 8194-8195.

(15) Knapp, M. J.; Klinman, J. P. "Environmentally coupled hydrogen tunneling - Linking catalysis to dynamics," Eur. J. Biochem. 2002, 269, 3113-3121.

(14) Knapp, M. J.; Rickert, K.; Klinman, J. P. "Temperature-dependent isotope effects in soybean lipoxygenase-1: Correlating hydrogen tunneling with protein dynamics," J. Am. Chem. Soc. 2002, 124, 3865-3874.

(13) Knapp, M. J.; Seebeck, F. P.; Klinman, J. P. "Steric control of oxygenation regiochemistry in soybean lipoxygenase-1," J. Am. Chem. Soc. 2001, 123, 2931-2932.

(12) Krzystek, J.; Telser, J.; Knapp, M. J.; Hendrickson, D. N.; Aromi, G.; Christou, G.; Angerhofer, A.; Brunel, L. C. "High-frequency and -field electron paramagnetic resonance of high-spin manganese(III) in axially symmetric coordination complexes," Appl. Magn. Reson. 2001, 21, 571-585.

(11) Maes, E. M.; Knapp, H. J.; Czernuszewicz, R. S.; Hendrickson, D. N. "Ligand conformational effects on the resonance Raman signature of [Fe4S4(SAryl)4]2- clusters," J. Phys. Chem. B 2000, 104, 10878-10884.

(10) Knapp, M. J.; Krzystek, J.; Brunel, L. C.; Hendrickson, D. N. "High-frequency EPR study of the ferrous ion in the reduced rubredoxin model [Fe(SPh)4]2-," Inorg. Chem. 2000, 39, 281-288.

(9) Brechin, E. K.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. "New hexanuclear and octanuclear iron(III) oxide clusters: octahedral [Fe6O2]14+ species and core isomerism in [Fe8O4]16+ complexes," Inorg. Chim. Acta 2000, 297, 389-399.

(8) Aromi, G.; Knapp, M. J.; Claude, J. P.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. "High-spin molecules: Hexanuclear Mn-III clusters with [Mn6O4X4]6+ (X = Cl-, Br-) face-capped octahedral cores and S=12 ground states," J. Am. Chem. Soc. 1999, 121, 5489-5499.

(7) Knapp, M. J.; Krzystek, J.; Brunel, L. C.; Hendrickson, D. N. "High-field EPR study of resonance-delocalized [Fe2(OH)3(tmtacn)2]2+," Inorg. Chem. 1999, 38, 3321-3328.

(6) Grant, C. M.; Stamper, B. J.; Knapp, M. J.; Folting, K.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. "Syntheses, crystal structures and properties of mononuclear chromium(III) and dinuclear vanadium(III) and copper(II) complexes with a bis-bipyridyl ligand," J. Chem. Soc. Dalton 1999, 3399-3405.

(5) Grant, C. M.; Knapp, M. J.; Streib, W. E.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. "Dinuclear and hexanuclear iron(III) oxide complexes with a bis(bipyridine) ligand: A new [Fe6(m3-O)4]10+ core," Inorg. Chem. 1998, 37, 6065-6070.

(4) Seela, J. L.; Knapp, M. J.; Kolack, K. S.; Chang, H. R.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. "Structural and magnetochemical properties of mono-, di-, and trinuclear Manganese(III) dithiolate complexes," Inorg. Chem. 1998, 37, 516-525.

(3) Grant, C. M.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. "A new structural type in iron carboxylate cluster chemistry via use of bis-bipyridine ligands: [Fe6O4Cl4(O2CPh)4L-2][FeCl4]2," Chem. Comm. 1998, 1753-1754.

(2) Aromi, G.; Claude, J. P.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. "High-spin molecules: Hexanuclear [Mn6O4Cl4(Me2dbm)6] (Me2dbmH = 4,4 '-dimethyldibenzoylmethane) with a near tetrahedral [Mn6O4Cl4]6+ core and a S=12 ground state," J. Am. Chem. Soc. 1998, 120, 2977-2978.

(1) Grillo, V. A.; Knapp, M. J.; Bollinger, J. C.; Hendrickson, D. N.; Christou, G. "Bis(bipyridine) ligands in manganese carboxylate cluster chemistry: Self-assembly of a cluster complex with two butterfly-like [Mn4(m3-O)2]8+ cores," Angew. Chem. Int. Ed. 1996, 35, 1818-1820.