Curriculum Vitae

Michael J. Knapp

Dept. of Chemistry c/o Klinman Group
University of California, Berkeley
Berkeley, CA 94720
(510) 642-7450


Ph.D., Chemistry (Emphasis: Physical Inorganic Chemistry)         1998
University of California, San Diego Advisor: Professor David N. Hendrickson

Thesis title: "Spectroscopic Properties of Iron-Sulfur Model Systems: High-Field EPR and Electronic Structure Calculations"

                    B.S., Biology (Major: Biochemistry and Cell Biology)         1993
                    University of California, San Diego
                                        Advisor: Professor Paul Saltman

Research Experience:

NIH Postdoctoral Fellow, University of California, Berkeley 1998-present
Advisor: Professor Judith P. Klinman Accomplishments: Supervised undergraduate researchers. Discovered a protein channel that directs stereo- and regio-specificity in enzymatic oxidations. Developed quantum-mechanical models for kinetic isotope-effects.

Skills: SDS PAGE, enzyme assays, bacterial expression, protein purification. DNA isolation, PCR, site-directed mutagenesis. Steady-state kinetics. Single turnover kinetics. Molecular modelling.

Graduate School

Research Assistant, University of California, San Diego 1994-1998

Advisor: Professor David N. Hendrickson Accomplishments: Demonstrated that ligand-conformation alters the electronic structure of iron-sulfur clusters. Developed magnetic coupling schemes for metal clusters. Determined electronic structure of mononuclear and dinuclear transition-metal complexes.

Skills: EPR, Optical spectroscopy. Magnetic susceptibility and relaxation. Electronic structure calculations. Anaerobic synthesis.

Research Interests: Bio-Inorganic Chemistry. Enzymology and electronic structure of non-heme Fe cofactors. Magnetic and spectroscopic studies of transition-metal compounds. Hydrogen tunneling and C-H activation chemistry. Teaching Experience: Teaching Assistant 1993-1994

University of California, San Diego

Directed analytical chemistry lab sections.

Led general chemistry recitation sections.

Teaching Assistant 1989-1992

San Diego Unified School District, San Diego, California

Prepared and instructed science labs for grades 7-12.

Awards and Memberships:

NIH Postdoctoral Fellowship

NIH Predoctoral Trainee

Member, American Association for the Advancement of Science Member, American Chemical Society

Division of Inorganic Chemistry

Division of Biological Chemistry