Introduction
- Phosphotriesterase activity first detected in Pseudomonas
diminuta and Flavobacterium sp.1
- Phosphotriesterase has no known "natural" substrates;
however it hydrolyzes a number of phosphotriesters, including:2
- Hydrolysis of paraoxon has a reported rate constant Vmax/Km
of >4x107 M-1 s-1, nearly diffusion
controlled1