Education:
Ph.D. University of Massachusetts, MA; 1999
Current position: NIH Postdoctoral Fellow, California Institute of Technology
"Electronic Communication in Structurally Constrained Cyclopenta-Fused Polyaromatics. An Experimental and Density Functional Investigation" A. Niemz, L. Steffen, B. Plummer, A. Cuello, V. Rotello*, J. Am. Chem. Soc., submitted for publication.
"Divergent Surface Functionalization Using Acid Fluoride-Functionalized Self-Assembled Monolayers" A. Niemz, E. Jeoung, A. Boal, R. Deans, V. Rotello Langmuir, in press.
"Supramolecular Models of Flavoenzyme Activity" C. McIntosh, A. Niemz, V. Rotello Flavins and Flavoproteins 99, Ghisla, S.; Macheroux, P.; Kroneck, P.; Sund, H. eds.Agency for Scientific Publishing: Berlin, 1999, 67-70
"Control of One- Versus two-Electron Reduction of Ubiquinone Via Redox-Dependent Recognition" M. Greaves, A. Niemz, V. Rotello, J. Am. Chem. Soc., 1999, 121, 266-267.
"From Enzyme to Molecular Device. The Interdependence of Recognition and Redox Processes" A. Niemz, V. Rotello,* Accts. Chem. Res., 1999,32,44-53.
"Electrochemical Control of Recognition Processes. A Three-Component Molecular Switch" R. Deans, A. Niemz, E. Breinlinger, V. Rotello,* J. Am. Chem. Soc., 1997, 119, 10863-10864.
"Modification of Spin Density Distribution via Specific Hydrogen Bond Interactions: an Experimental, UHF and Density Functional Study" A. Niemz, V.Rotello,* J. Am. Chem. Soc., 1997, 119, 6833-6836.
"UV-Vis Spectroelectrochemistry of Flavins in Aprotic Organic Solvents" A. Niemz, V. Rotello,* Flavins and Flavoproteins '96, Steveneson, K.; Massey, V.; Williams, C.; eds. Univ. of Calgary: Calgary, 1997, 159-162.
"Synthetic Models for Flavoenzyme Activity: Modification of Flavin Redox Properties Through Hydrogen Bonding" E. Breinlinger, A. Niemz and V. Rotello,* Flavins and Flavoproteins '96, Steveneson, K.; Massey, V.; Williams, C.; eds. Univ. of Calgary: Calgary, 1997, 123-126.
"Model Systems for Flavoenzyme Activity: One and Two Electron Reduction of Flavins in Aprotic Hydrophobic Environments" A. Niemz, J. Imbriglio, V. Rotello,* J. Am. Chem. Soc., 1997, 119, 892-897.
"Model Systems for Flavoenzyme Activity. The Effects of Specific Hydrogen Bonds on the 13C and 1H NMR of Flavins" A. Niemz and V. Rotello,* J. Mol. Rec., 1996, 9, 158.
"Model Systems for Flavoenzyme Activity. Stabilization of the Flavin Radical Anion Through Specific Hydrogen Bond Interactions" E. Breinlinger, A. Niemz, V. Rotello,* J. Am. Chem. Soc., 1995, 117, 5379.
Presentations:
1998: "A Three component-Two Pole Switch", 216th National Meeting of the American Chemical Society, Boston, MA August, 1998.
1996: Flavins and Flavoproteins '96, Calgary, Canada
Eric Breinlinger
Ph.D. University of Massachusetts, MA; 1998
Current Position: Medicinal Chemistry, Albany Molecular
Publications:
"Modulation of Flavin Recognition and Redox Properties through Donor Atom-p Interactions" E. Breinlinger, C. Keenan, V. Rotello,* J. Am. Chem. Soc., 1998, 120, 8606-8609.
"Electrochemical Control of Recognition Processes. A Three-Component Molecular Switch" R. Deans, A. Niemz, E. Breinlinger, V. Rotello,* J. Am. Chem. Soc., 1997, 119, 10863-10864.
"Synthetic Models for Flavoenzyme Activity: Modification of Flavin Redox Properties Through Hydrogen Bonding" E. Breinlinger, A. Niemz and V. Rotello,* Flavins and Flavoproteins '96, Steveneson, K.; Massey, V.; Williams, C.; eds. Univ. of Calgary: Calgary, 1997, 123-126.
"Model Systems for Flavoenzyme Activity. Modulation of Flavin Redox Potentials Through p-stacking Interactions" E. Breinlinger and V. Rotello,* J. Am. Chem. Soc., 1997, 119, 1165-1166.
"Model Systems for Flavoenzyme Activity. Stabilization of the Flavin Radical Anion Through Specific Hydrogen Bond Interactions" E. Breinlinger, A. Niemz, V. Rotello,* J. Am. Chem. Soc., 1995, 117, 5379.
"Selective and Efficient Transport of Riboflavin Through a Liquid Membrane" T. Lambert, E. Breinlinger, V. Rotello,* J. Org. Chem., 1995, 60, 2646.
Presentations:
"Modulation of Flavin Redox Potential through p-Stacking Interactions" Gordon Research Conference on Physical Organic Chemistry, Holderness, N.H., June, 1997.
"Synthetic Models of Flavoenzyme Activity", 208th National Meeting of the American Chemical Society, Washington D.C., August, 1994.
"Stabilization of Flavin Radical Anions through Hydrogen Bonding", 24th Northeast Regional Meeting, Burlington VT, June 1994.
Robert Deans
Ph.D. University of Massachusetts, MA; 1998
Current Position: Postdoctoral Associate, Massachusetts Institute of Technology (T. Swager)
Publications:
"Recognition-Mediated Unfolding of a Polymeric "Molten Globule"" R. Deans, F. Ilhan, V. Rotello, J. Am. Chem. Soc., submitted for publication.
"Electrochemical Control of Recognition Processes. A Three-Component Molecular Switch" R. Deans, A. Niemz, E. Breinlinger, V. Rotello,* J. Am. Chem. Soc., 1997, 119, 10863-10864.
"Model Systems for Flavoenzyme Activity. Molecular Recognition of Flavin at the Polymer-Liquid Interface" Deans, R.; Rotello, V. M. J. Org. Chem. 1997, 62, 4528.
"Model Systems for Flavoenzyme Activity. Regulation of Flavin Recognition via Modulation of Receptor Hydrogen-Bond Donor-Acceptor Properties" Deans, R.; Cooke, G.; Rotello, V. M. J. Org. Chem. 1997, 62, 836.
"Model Systems for Flavoenzyme Activity. 2-Aminopyridines as Spectroscopic Models for Flavoenzyme Active Sites" Deans, R.; Rotello, V. M. Tetrahedron Lett. 1996, 37, 4435.
Presentations:
1997: Department of Chemistry, Chemical Education Symposium, University of Massachusetts, Amherst, MA.
1995: Department of Chemistry, Research Symposium, University of Massachusetts, Amherst, MA.
1995: American Chemical Society, 210th National Meeting, Chicago, IL.
1994: American Chemical Society, 24th N.E. Regional Meeting, Burlington, VT.
Michael Greaves
Ph.D. University of Massachusetts, MA; 1998
Current Position: Postdoctoral Associate, University of Texas (K. Balkus)
Publications:
"Model Systems for Flavoenzyme Activity. Aromatic Stacking in Silicate Matrices" M. Greaves, T. Galow, V. Rotello, J. Chem. Soc., Chem. Comm., 1999, 169-170.
"Control of One- Versus two-Electron Reduction of Ubiquinone Via Redox-Dependent Recognition" M. Greaves, A. Niemz, V. Rotello, J. Am. Chem. Soc., 1999, 121, 266-267.
"Specific Recognition of Flavin in a Sol-Gel Matrix" M. Greaves, V. Rotello, Sol-Gel Optics IV, Dunn, B.; Mackezie, J.; Pope, E.; Schmidt, H.; Yamane, M., eds, SPIE:Bellingham, 1997, 433-441.
"Model Systems for Flavoenzyme Activity.Hydrogen Bond Recognition of FMN in a Sol-Gel Matrix" M. Greaves, V. Rotello,* J. Am. Chem. Soc., 1997, 119, 10569-10572.
"Covalent Attachment of C60 to a Furan-Substituted Resin" B. Nie, K. Hasan, M. Greaves, V. Rotello,* Tetrahedron Letters, 1995, 3617.
"Reversible Covalent At tachment of C60 to a Polymer Support" K.Guhr, M. Greaves, V. Rotello,* J. Am. Chem. Soc., 1994, 116, 5997.
Presentations: .
1997: Sol-Gel Optics IV, (SPIE's Optical Science, Engineering and Instrumentation '97), San Diego, CA.
1996: Departmental Research Symposium, University of Massachusetts.
1995: American Chemical Society 210th National Meeting, Chicago, IL.
1994: American Chemical Society 207th National Meeting, Washington D.C.
1994: North East Regional American Chemical Society 24th Meeting, Burlington, VT.