Chem 728 - Physical Biochemistry

TTh 9:30-10:45, GSMN 51

Course Home Page: http://www.chem.umass.edu/~cmartin/Courses/Ch728


Syllabus | Instructor | News | Objectives | Texts | Grading | Lec Notes 2000

Instructor:    Craig T. Martin

Office hours by appointment.

OfficePhoneEMail
Craig Martin LGRT 403D 545-3299 CMartin@chem.umass.edu

Recent news:


Course objectives

Biological molecules underlie all of life and represent chemistry far more complex than most chemists encounter. On the other hand, they of course follow all of nature's pinciples (chemistry), and so can be approached from that perspective. The principles of physical chemistry are the key to understanding both the behavior of these molecules (folding, binding, catalysis) and the techniques available for studying their structure and mechanism.

This course aims to convey how these principles are applied to biological systems. The course will emphasize problem solving, with the goal of understanding, not memorization. Computer resources will introduce us to tools for understanding structure, complex binding equilibria, and enzyme kinetics.


Texts

Required van Holde, Johnson, & Cho, "Principles of Physical Biochemistry," 1998, Prentice Hall.

Chem 728 lecture notes
Supplemental Cantor & Schimmel, "Biophysical Chemistry," 1980(!), Volumes I-III, W. H. Freeman.

Sanders & Hunter, "http://www.oup-usa.org/search97cgi/s97_cgi?action=View&VdkVgwKey=%2E%2E%2F%2E%2E%2F%2E%2E%2F%2E%2E%2F%2E%2E%2Fdata%2Finfobox%2Fwww%2Fusa%2Fisbn%2F0198555679%2Ehtml&DocOffset=1&DocsFound=2&QueryZip=catalog+%3Ccontains%3E+general+and+description+%3 TARGTex>Modern NMR Spectroscopy," 1993, Oxford Univ Press.

Others: your favorite PChem texts, see library reserves for Chem 471-475 <

The texts are on reserve in the Physical Sciences Library


Grading / Requirements

Exams are take-home, but MUST be worked on independently. Honesty is critical and violations will not be tolerated.

Problem sets can and should be worked on collaboratively

20% Problem Sets and Projects
20% Exam I
20% Exam II
20% Exam III
20% Exam IV


Instructor | News | Objectives | Texts | Grading