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Welcome to the Chen Research Group!
We use computer modeling as a primary tool to understand how
biomolecules perform their biological functions, via stable
3D structures, or, equally important, lack of stable structures.
Current focus areas:
- Intrinsically disordered proteins: structure, function and disease
- Multi-scale simulations of biomolecular condensates
- Coarse-grained modeling of flexible RNAs
- Gating and regulation of ion channel proteins
- Advanced sampling techniques and implicit solvent models
- Statistical learning and prediction of protein function
学而不思则罔，思而不学则殆 (孔子）
Learning without (critical) thinking leads to perplexity,
while thinking without learning ends in danger (Confucius).
Open Positions:
We constantly look for bright undergraduate and graduate
students. Students expect to receive training and pursue research in
computational biochemistry and biophysics, but will also have
opportunities to work in experimental labs. General background and
interest in biochemistry, biophysics, and/or computer programming is
necessary. We will consider strong candidates for
postdoctoral positions. Please direct your inquiry to Jianhan Chen via
.
Life Science Laboratories, Suite S585
240 Thatcher Way, Amherst, MA 01003-9364
Phone: 413-545-3386 (o) -3365(lab)
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